Official NUC CCMAS syllabus

PCH 402 — Medicinal Chemistry I

PCH department course · Nigerian universities

What you'll be able to do (official learning outcomes)

• describe physical approaches in drug design
• explain concepts of isosterism; and
• describe usefulness of enzymes in biotransformation

Course contents

Drug design. Physicochemical approaches to drug design. Historical, Free-Wilson and Hansch approaches. The concept of isosterism. Bio-isosterism as a tool in drug design. Structure-Activity Relationship in drug design. Antimetabolite and pro-drug approach to design of new drugs. Drug metabolism. Enzymes in biotransformation.

Source: the Nigerian Universities Commission (NUC) Core Curriculum and Minimum Academic Standards (CCMAS). StudyOps loads this syllabus automatically when you study PCH 402.

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• PCH 201 · Inorganic Pharmaceutical Chemistry
• PCH 202 · Physical Pharmaceutical Chemistry I
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• PCH 301 · Organic Pharmaceutical Chemistry
• PCH 302 · Organic Pharmaceutical Chemistry II
• PCH 401 · Pharmaceutical Analysis I
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