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What you'll be able to do (official learning outcomes)
explain the concept of genetic variation (continuous and discontinuous) among the general population
discuss the significance of genetic polymorphism in the development, progression and treatment of human disease
describe the models of drug distribution and elimination
describe the factors which determine the time-course of systemic accumulation of a drug administered by infusion or multiple doses
use the pharmacokinetic parameters to determine loading and maintenance doses of specific drug regimens; and
identify the factors that affect hepatic and renal clearance (blood flow, protein binding, intrinsic clearance etc)
Course contents
Pattern of transmission of single gene trait. Hardy-Weinberg law conditions for its validity, application. On concepts of continuous and discontinuous variation. Pharmacogenetics (drug metabolism, tissue metabolism and receptor alterations). Compartment models (one and two) Sciences 708 New kinetics after intravenous and oral dosing.
Source: the Nigerian Universities Commission (NUC) Core Curriculum and Minimum Academic Standards (CCMAS). StudyOps loads this syllabus automatically when you study PHA 302.